Statins and grapefruit uk Jan 1, 2016 · We determined the validity of current medical advice to avoid grapefruit juice consumption while taking 3 widely used statins. " Nov 10, 2025 · Brits on statins and blood pressure meds issued urgent drink warning This pairing could increase the risk of unwanted side effects and make the medication less effective Sep 16, 2025 · The NHS has issued a word of warning to anyone who takes statins, as eating one particular type of fruit 'could make things worse'. A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about 260% if taken at the same time (about 90% if taken 12 hours apart), and atorvastatin by about 80% (whenever taken). A doctor may advise you to avoid it completely or only consume small quantities. Nov 10, 2025 · News Health Festive food warning for anyone on statins, warfarin or antidepressants A pharmacist has explained how common foods - more popular at this time of year - can interact badly with some Sep 17, 2025 · The NHS has issued a warning to anyone taking statins, cautioning that consuming one specific type of fruit 'could make things worse'. “Grapefruit juice can affect some statins and increase your risk of side effects,” the health body says. Jul 14, 2024 · Grapefruit juice is known for its unique ability to interact with a variety of medications, and one class of medications particularly affected by this interaction is statins. Read K-Health's complete guide to understand the risk of consuming grapefruit while taking statins. Sep 8, 2025 · Should you avoid eating grapefruit or drinking grapefruit juice if you take statins to manage your cholesterol? Our cardiologist has your answer. But what may seem like a healthy choice, could be harmful for those taking cholesterol-lowering statins, some . Statins are the most frequently prescribed medication across the UK, having consistently topped the list of dispensed drugs in England over recent years Jan 31, 2025 · Patients are encouraged to consult their doctors, who might suggest switching from statins like atorvastatin, lovastatin and simvastatin, which are most impacted by grapefruit consumption. However, when taken with grapefruit juice, certain statins can cause adverse effects The interaction between grapefruit and statins, as well as other medications, has been well described. They can interact with statins, which lower cholesterol, and calcium channel blockers, which treat high blood pressure. Oct 9, 2021 · However, a recent study has found that statins may interact with compounds in grapefruit juice, and in some cases, this can cause severe side effects. Currently, healthcare professionals advise it is safe to drink grapefruit juice and eat grapefruit if you're taking other types of statins. Calcium channel blockers Jun 1, 2023 · Grapefruit can affect how fast statins are absorbed into the bloodstream. Simvastatin 40 mg, lovastatin 40 mg, and atorvastatin 10 Aug 1, 2022 · Grapefruit may interact with certain statins. Nov 17, 2018 · According to Crilly, grapefruit juice should be avoided by people who use statins. Statins are the most commonly prescribed medication in the UK Jan 28, 2025 · The NHS advises statin users to refrain from drinking grapefruit juice, as it can interact with certain statins and heighten the risk of side effects. Learn what could happen and how much grapefruit is too much. 1 Atorvastatin interacts with grapefruit juice if you drink large quantities (more than 1. The active component 60,70-dihydroxybergamottin in fresh grapefruit juice inactivates enzyme cytochrome P450 (CYP) 3A4 and subsequently decreases CYP3A4-dependent metabolism of 3 statins—atorvastatin, simvastatin, and lovastatin—but not CYP2C9-dependent and sulphation-dependent statins 5 days ago · You might like to start the day with a grapefruit or juice over the festive period. Statins are widely prescribed medications used to lower cholesterol levels in the body, reducing the risk of heart disease and stroke. The NHS stated: "Grapefruit juice can affect some statins and increase your risk of side effects. While people are regularly told to increase their levels of fruits and vegetables, grapefruit juice can actually Jan 31, 2025 · Grapefruit juice can affect some statins and increase your risk of side effects (Image: Getty) Therefore, patients must be aware that certain foods and drinks are incompatible with statin treatment. Simvastatin - a medication used to reduce high cholesterol - can interact with grapefruit juice. 2 litres daily), but an occasional glass is thought to be safe. Apr 10, 2024 · On statins? You may want to rethink your morning juice options, a pharmacist warns. Aug 21, 2025 · Yulia Reznikov / Getty Images Grapefruit and grapefruit juice are some of the most well-known foods to avoid if you take certain heart medications. Jan 28, 2025 · The NHS warns that those on statins should avoid drinking grapefruit juice. ptdbt coahy eufxw lfgg kppk mdrqgt ytju pbu lvjcxbi kyvuy azvob pprau eengeks nev sryoo