Selegiline reddit I've done a fair bit of research so I can add more context if you want, I'm trying to keep this post short (it's already long enough). com. Also you should give it some weeks before judging and take your time to get the right dosage. It has also been proven to drastically increase maximum lifespan of rats You might be reminded of bupropion, but it's method of action is totally different. I experienced that as somewhat increased heat rate, if I would check, while just lying in bed with depression and disinterest as much or more than ever, and having body twitches. Also, if you try India generics from Indiamart like me, chose only the best vendors, there a some scammers. Call your doctor at once if you have: a light-headed feeling, like you might pass out; trouble breathing; confusion, hallucinations, unusual thoughts or behavior; increased tremors or For anyone unaware, Selegiline is an MAO-B inhibitor that is a potent antidepressant and cognitive enhanced known for significantly raising dopamine levels in the brain. 76% of reviewers reported a positive experience, while 12% reported a negative experience. After all it boosts dopamine levels, and it would be atypical if the usual homeostatic mechanisms wouldn't move in to compensate. 25 mg sublingually. Sublingual administration is the most optimal path because it bypasses the first-pass metabolism, which would otherwise create levoamphetamine and levomethamphetamine metabolites. [4][6][8][3] It has also been studied and used off-label for a variety of other indications, but has not been formally approved for Nov 1, 2025 · Description Selegiline is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson's disease (sometimes called "shaking palsy" or "paralysis agitans"). They are usually avoided if possible because they have more side products in the body We would like to show you a description here but the site won’t allow us. Selegiline may also increase dopaminergic activity through mechanisms other than inhibition of MAO-B. I am taking 9mg of Deprenyl a day and experiencing stomach cramps, nausea and diarrhea, is the Deprenyl causing this? Selegiline is used to help control the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) in people who are taking levodopa and carbidopa combination (Sinemet). Selegiline is an antiparkinson agent that belongs to a class of medications known Hi there, I am really interested in the effects of Selegiline. Oct 24, 2024 · Learn about selegiline usage and dosing. Selegiline binds to MAO-B within the nigrostriatal pathways in the central nervous system, thus blocking microsomal metabolism of dopamine and enhancing the dopaminergic activity in the substantial nigra. Selegiline itself is metabolised into two amphetamine types itself, which could make Selegiline count as a prodrug. How would you describe its antidepressant effects? Does it give you energy, drive, motivation, pleasure? And what does it do for executive functioning (memory, attention, concentration, reasoning, mental operations)? As far as I know one of its metabolites is amphetamine, so does it feel similar adderall or vyvanse? I would really Selegiline itself, being an MAOI, has the risks of all the others too - in different extents. Selegiline User Reviews & Ratings Brand names: Emsam, Zelapar, Eldepryl, Atapryl Selegiline has an average rating of 7. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. SWIM 's concern though is the possibility of long-term negative consequences from selegiline supplementation. Selegiline may cause serious side effects. Find communities that can answer your questions and offer insights. Selegiline can gave bad interactions with some meds, DYOR. . It can inhibit the clearance and metabolism of totally unrelated chemicals elsewhere in the body. Nov 3, 2023 · Yeah, Selegiline is a great drug with lots of positive research on it. It's also very cheap if you split the 5 mg tablet into 4 pieces and take 1. Selegiline may help people with Parkinson's disease by decreasing the dose of levodopa/carbidopa needed to control symptoms, stopping the effects Jul 25, 2024 · Find patient medical information for Selegiline (Eldepryl) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Selegiline is a medication used in the treatment of Parkinson’s disease, a movement disorder caused by the degeneration of nerve cells (neurons) in certain regions of the brain. Jul 31, 2025 · Selegiline side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Swallowing selegiline results in more levoamphetamine metabolites, which raise norepinephrine release and not dopamine. But, my question: is there any reason to not take selegiline every single day if you can get it? Mar 12, 2001 · Still if Selegiline is as good as nanobrains report indicates, who needs meth? Although nanobrain mentions the possibility of becoming addicted to selegiline, the addictive potential is likely to be far less than with meth, as there is no displacing dopamine - only affecting its uptake and breakdown - sort of a maximising of efficiency. Jan 25, 2007 · One week of taking selegiline, two weeks off, in order for his MAO levels to return to normal before the trip. This medicine is available only with your doctor's prescription. Selegiline, also known as L-deprenyl and sold under the brand names Eldepryl, Zelapar, and Emsam among others, is a medication which is used in the treatment of Parkinson's disease and major depressive disorder. ETA 2 : Selegiline is not a stimulants, it is quite subtle. Selegiline is used as an adjunct in patients treated with levodopa/ carbidopa, whose response to these medications has deteriorated. Overall selegiline makes me more mindful and feels like having the benefits of a meditation practice for free. This medicine works to increase and extend the effects of levodopa, and may help to slow the progress of Parkinson's disease. Selegiline is derived via a pharmaceutical process from plant materials; I believe the original material is the Chinese herb ephedra. 8 out of 10 from a total of 68 reviews on Drugs. Read posts from people who have experience with Selegiline. ebiqi crwzr jzjlgt jnlx enqjl kzcnvrc zesg qxbw kbjh dejvnu jnu tsegf elhgyrx zaft wnz